1. Harlequin Ichthyosis
TEN is identified as a severe allergic reaction. The allergic reaction is usually in response to an infection or a medication. TEN causes flu-like symptoms over a several day period. Inflamation of the mucous membranes then occurs. A rash covers the skin, killing the uppermost layer of skin. The dead skin will shed. This occurs over 30% of the body and can be fatal. More than a quarter of the people afflicted with this painful condition die from some type of infection.
7. Scleroderma
This skin disease afflicts newborn babies. It is a rare skin disease,
believed to be caused by a gene mutation, which usually results in death
within two days from birth. Harlequin Ichthyosis or HI causes
the skin to dry out and from hard plaques shaped like diamonds. When the
baby is born, the infant appears to be wearing a coat of armor. The
condition severely restricts the newborn's movements.
HI causes complications which are attributed to the newborns deaths. The
babies experience feeding problems. These infant are also susceptible
to both respiratory diseases and bacterial infections. Fortunately, the
level of care has improved substantially which in turn has increased the
survival rate for babies born with this devastating skin disease.
2. Epidermolysis Bullosa
Epidermolysis Bullosa is a group of hereditary skin disease.
There are three major types with several subsets. The skin disease has a
range of severity. The skin disease causes the skin to blister with only a light torch. Individual with more severe case of Epidermolysis Bullosa with
suffer with glistering of the mouth and esophagus too. Some types of
this disease can cause the toes and fingers to fuse giving the
appearance of webbing. Severe scaring in another effect.
There is no cure for this deadly skin disease. Victims of skin
conditions have to endure various courses of treatment, dependent on the
severity of their conditions. Some afflicted with this skin disease
must obtain food through a feeding tube to prevent infections. Surgeries
are often performed to dilate the esophagus and to remove the scar
tissue from the blistering.
3. Ehlers-Danlos Syndrome
Ehlers-Danlos Syndrome is a hereditary conditions. It is caused
by abnormalities in the collagen. This skin disease causes the skin to
be extremely stretchy (hyper elasticity) and lax. Persons afflicted with
Ehlers-Danlos Syndrome will also suffer with tissue weakness and easy bruising. Weak joints are also characteristic of this skin disease.
As with other skin disease, the severity of the symptoms experienced by an individual afflicted with Ehlers-Danlos Syndrome
depends on the type the person has. Some types of this disease will
cause hemorrhaging and can result in the rupturing of arteries. An
occurrence of this type will result in the person's death.
4. Methicillin-resistant Staphylococcus (AKA MRSA)
MRSA is labeled the "super bug". This potentially deadly
skin infection begins as small red bumps. The bumps look similar to
pimples or bug bites. These small bumps evolve into deep and painful
abscesses. The bacteria are confined into the skin but can gain access
into the body. Once in the body, MRSA causes infections in the blood,
heart, lungs, bones, and joints.
Treatment options for MRSA include surgery and certain antibiotics.
Surgery is performed to drain the wounds that become open abscesses and
place the person at risk for life threatening infections. MRSA is
resistant to almost all antibiotics. The bacteria have adapted defenses
to combat what was once a lethal toxin to the infection. Only two
antibiotics are strong enough to combat MRSA, vancomycin and linezolid.
5. Toxic Epidermal Necrolysis (AKA TEN)
TEN is identified as a severe allergic reaction. The allergic reaction is usually in response to an infection or a medication. TEN causes flu-like symptoms over a several day period. Inflamation of the mucous membranes then occurs. A rash covers the skin, killing the uppermost layer of skin. The dead skin will shed. This occurs over 30% of the body and can be fatal. More than a quarter of the people afflicted with this painful condition die from some type of infection.
6. Basal cell carcinomas and Squamous cell carcinoma.
Both of these skin diseases are forms of skin cancer. Basal cell carcinomas occur in the basal layer of skin. The cancer damages the tissue and causes scarring. This cancer doesn't metastasize.Squamous cell carcinoma occurs in the squamous cells,
hence the name. Squamous cells from the skin surrounding the internal
organs. The cancer does metastasize. The cancer can spread to the
organs. This type of cancer kill at least 2500 people in the US each
year.
7. Scleroderma
Scleroderma causes abnormal growth of connective tissue. The skin
hardens and tightens. Scar tissue then forms on the skin and other
organs in the body. This condition is believed to be an autoimmune
disease. The more severe forms of Scleroderma can cause the lung and
heart tissue to thicken also. When this occurs, death often results.
8. Pemphigus
Pemphigus is a group of chronic skin diseases. The skin disease is characterized by open sores
caused by blisters. The sores can lead to infections. Severe cases of
Pemphigus can cause lesions on the lungs and may lead to lung disease.
This skin disease is thought to be an autoimmune disorder.
Pemphigus is treated with medications. Corticosteroids are most often
prescribed. Treatments also include antibiotics or immunosuppressants.
Some people require hospitalization to care for the wounds. Severe cases
of Phempigus can result in death.
9. Leishmaniasis
Leishmaniasis is reported to have afflicted around 12 million
people and is considered to be endemic. The disease is transmitted by
sand flies. When the sand fly bites, they transfer the skin disease. A
sore usually appears on the bite and scars the skin. The disease then
causes skin lesions and ulcers.
Tissue damage occurs in the mouth and nose. Infections attack the
liver, bone, marrow and spleen. Other organs can also be infected.
10. Herpes Gladiatorum or Scrumpox
Scrumpox is a skin disease caused by a strain of the herpes
virus. The skin disease causes cold sores. Sore throats, blisters on the
face, arms, neck, and legs. As with many of the other skin disease,
infection can be a complication of the blisters and sores. The infection
can then lead to death. Scrumpox is spread through skin contact and is
extremely contagious.
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